{"id":410,"date":"2024-06-22T14:04:38","date_gmt":"2024-06-22T05:04:38","guid":{"rendered":"https:\/\/wwp.ait.tokushima-u.ac.jp\/tokudai-a4\/?page_id=410"},"modified":"2024-06-25T15:50:46","modified_gmt":"2024-06-25T06:50:46","slug":"plant-group","status":"publish","type":"page","link":"https:\/\/wwp.ait.tokushima-u.ac.jp\/tokudai-a4\/?page_id=410","title":{"rendered":"Plant Research Group"},"content":{"rendered":"\n

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\u5fc3\u6750\u6297\u83cc\u6210\u5206\u30ce\u30eb\u30ea\u30b0\u30ca\u30f3\u306e\u751f\u5408\u6210\u7814\u7a76<\/a><\/strong><\/h2>\n\n\n\n
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\u3000\u3000\u300c\u5fc3\u6750\u306e\u5f62\u6210\u300d\u306f\u6a39\u6728\u7279\u6709\u306e\u73fe\u8c61\u3067\u3059.  \u5fc3\u6750\u3068\u306f\u4e38\u592a\u306e\u4e2d\u5fc3\u90e8\u306b\u898b\u3089\u308c\u308b\u6750\u8272\u306e\u5c11\u3057\u6fc3\u3044\u9818\u57df\u3067\u3042\u308a, \u4e00\u65b9, \u5fc3\u6750\u306e\u5916\u5074\uff08\u6a39\u76ae\u5074\uff09\u306e\u6750\u8272\u306e\u6de1\u3044\u9818\u57df\u3092\u8fba\u6750\u3068\u3088\u3073\u307e\u3059. \u3055\u3089\u306b\u5fc3\u6750\u3068\u8fba\u6750\u306e\u9593\u306b\u306f\u767d\u304f\u898b\u3048\u308b\u9818\u57df\u304c\u3042\u308a, \u305d\u308c\u3092\u79fb\u884c\u6750\uff08\u767d\u7dda\u5e2f\uff09\u3068\u3088\u3073\u307e\u3059. \u5fc3\u6750\u306f\u82e5\u3044\u6642\u306b\u306f\u5b58\u5728\u305b\u305a, \u6210\u9577\u306e\u3044\u3064\u306e\u6bb5\u968e\u304b\u306b\u5f62\u6210\u3055\u308c\u59cb\u3081\u307e\u3059\u304c, \u6a39\u7a2e\u306b\u3088\u3063\u3066\u5f62\u6210\u306e\u30bf\u30a4\u30df\u30f3\u30b0\u304c\u7570\u306a\u308b\u306a\u3069, \u672a\u3060\u306b\u4f55\u304c\u304d\u3063\u304b\u3051\u3067\u5fc3\u6750\u304c\u5f62\u6210\u3055\u308c\u59cb\u3081\u308b\u306e\u304b\u306f\u89e3\u660e\u3055\u308c\u3066\u3044\u307e\u305b\u3093. 
\u3000\u3000\u4e00\u822c\u306b\u5fc3\u6750\u306f\u8fba\u6750\u306b\u6bd4\u3079\u3066\u8150\u308a\u306b\u304f\u304f\u5f37\u5ea6\u304c\u9ad8\u3044\u3068\u3055\u308c\u3066\u304a\u308a, \u4e3b\u306b\u5efa\u7bc9\u6750\u306a\u3069\u3068\u3057\u3066\u53e4\u304f\u304b\u3089\u5229\u7528\u3055\u308c\u3066\u304d\u307e\u3057\u305f. \u305d\u306e\u8150\u308a\u306b\u304f\u3055\u3092\u3082\u305f\u3089\u3057\u3066\u3044\u308b\u306e\u304c,  \u5fc3\u6750\u90e8\u306b\u84c4\u7a4d\u3059\u308b\u69d8\u3005\u306a\u6297\u83cc\u6210\u5206\u3067\u3059. \u5fc3\u6750\u306b\u7279\u7570\u7684\u306b\u84c4\u7a4d\u3059\u308b\u6297\u83cc\u6210\u5206\u306e\u4e00\u7a2e\u3068\u3057\u3066\u300c\u30ce\u30eb\u30ea\u30b0\u30ca\u30f3\u300d\u3068\u3044\u3046\u5316\u5408\u7269\u7fa4\u304c\u3042\u308a\u307e\u3059. \u30ce\u30eb\u30ea\u30b0\u30ca\u30f3\u985e\u306f\u6297\u83cc\u6d3b\u6027\u306e\u307f\u306a\u3089\u305a, \u305d\u306e\u4ed6\u69d8\u3005\u306a\u751f\u7406\u6d3b\u6027\u304c\u3053\u308c\u307e\u3067\u306b\u5831\u544a\u3055\u308c\u3066\u304a\u308a, \u307e\u305f\u30ce\u30eb\u30ea\u30b0\u30ca\u30f3\u985e\u306e\u3042\u308b\u5316\u5408\u7269\u304c\u6749\u306e\u9ed2\u5fc3\uff08\u9ed2\u8272\u5316\u3057\u305f\u5fc3\u6750\uff09\u306e\u539f\u56e0\u7269\u8cea\u3068\u3057\u3066\u3082\u77e5\u3089\u308c\u3066\u3044\u307e\u3059. \u5fc3\u6750\u30ce\u30eb\u30ea\u30b0\u30ca\u30f3\u985e\u306f\u5fc3\u6750\u5f62\u6210\u306e\u6642\u671f\u3068\u9023\u52d5\u3057\u3066\u751f\u5408\u6210\u3055\u308c, \u8fba\u6750\u3067\u306f\u84c4\u7a4d\u305b\u305a, \u79fb\u884c\u6750\u304b\u3089\u5fc3\u6750\u306b\u304b\u3051\u3066\u6025\u6fc0\u306b\u84c4\u7a4d\u91cf\u304c\u5897\u52a0\u3057\u307e\u3059.
\u3000\u3000\u4e16\u754c\u7684\u306b\u3082\u30ce\u30eb\u30ea\u30b0\u30ca\u30f3\u985e\u306e\u751f\u5408\u6210\u7814\u7a76\u306f\u6570\u5c11\u306a\u304f, \u672a\u3060\u8b0e\u304c\u591a\u304f\u5b58\u5728\u3057\u3066\u3044\u307e\u3059. \u3053\u308c\u307e\u3067\u306b\u5f53\u7814\u7a76\u5ba4\u306e\u5c71\u6751\u3089\u306f\u9577\u5e74\u30ce\u30eb\u30ea\u30b0\u30ca\u30f3\u985e\u306e\u4e00\u7a2e\u3067\u3042\u308b\u30d2\u30ce\u30ad\u30ec\u30b8\u30ce\u30fc\u30eb\u306e\u751f\u5408\u6210\u7814\u7a76\u306b\u53d6\u308a\u7d44\u307f, \u69d8\u3005\u306a\u6210\u679c\u3092\u5831\u544a\u3057\u3066\u304d\u307e\u3057\u305f\uff08\u56f3\uff11, \u5f15\u7528\u6587\u732e \uff0a1\u301c4\uff09. \u30ce\u30eb\u30ea\u30b0\u30ca\u30f3\u985e\u306e\u751f\u5408\u6210\u306b\u95a2\u3059\u308b\u907a\u4f1d\u5b50\u306f, \u4eca\u306e\u3068\u3053\u308d\u30a2\u30b9\u30d1\u30e9\u30ac\u30b9\u304b\u3089\u552f\u4e00\u540c\u5b9a\uff08\uff0a3, 4\uff09\u3055\u308c\u3066\u3044\u308b\u306e\u307f\u3067, \u6a39\u6728\u304b\u3089\u306f\u3053\u308c\u3089\u907a\u4f1d\u5b50\u306f\uff11\u3064\u3082\u898b\u51fa\u3055\u308c\u3066\u3044\u307e\u305b\u3093. \u5f53\u7814\u7a76\u5ba4\u3067\u306f\u73fe\u5728, \u30b9\u30ae\u6728\u6750\u3067\u306e\u907a\u4f1d\u5b50\u767a\u73fe\u3092\u7db2\u7f85\u89e3\u6790\u3057, \u5fc3\u6750\u30ce\u30eb\u30ea\u30b0\u30ca\u30f3\u306e\u751f\u5408\u6210\u306b\u95a2\u4e0e\u3059\u308b\u907a\u4f1d\u5b50\u306e\u540c\u5b9a\u306b\u53d6\u308a\u304f\u3093\u3067\u3044\u307e\u3059. 
\u3000\u3000\u5c06\u6765\u7684\u306b\u5fc3\u6750\u306b\u7279\u7570\u7684\u306b\u84c4\u7a4d\u3059\u308b\u6210\u5206\u306e\u907a\u4f1d\u5b50\u7fa4\u3092\u660e\u3089\u304b\u306b\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u308c\u3070, \u5fc3\u6750\u5f62\u6210\u958b\u59cb\u306e\u304d\u3063\u304b\u3051\u3068\u306a\u308b\u8981\u56e0\u306e\u7279\u5b9a, \u5fc3\u6750\u6210\u5206\u3092\u5897\u5f37\u3057\u305f\u9ad8\u3044\u8010\u8150\u673d\u6027\u6728\u6750\u3092\u7b97\u51fa\u3059\u308b\u6a39\u6728\u306e\u4f5c\u51fa, \u307e\u305f\u6297\u83cc\u6210\u5206\u306e\u5b89\u4fa1\u304b\u3064\u5b89\u5b9a\u3057\u305f\u4f9b\u7d66\u306a\u3069\u306b\u3064\u306a\u304c\u308b\u3068\u671f\u5f85\u3055\u308c\u307e\u3059.<\/pre>\n\n\n\n
\uff1c\u5f15\u7528\u6587\u732e\uff1e
\uff0a\uff11, Suzuki, Yamamura, Shimada, Umezawa (2004) \"A heartwood norlignan, (E)-hinokiresinol, is formed from 4-coumaryl 4-coumarate by a Cryptomeria japonica enzyme preparation\" Chem Commun: 2838-2839
\uff0a\uff12, Suzuki, Nakatsubo, Umezawa, Shimada (2001) \"First in vitro norlignan formation with Asparagus officinalis enzyme preparation\" Chem Commun: 1088-1089
\uff0a\uff13, Suzuki, Yamamamura, Hattori, Nakatsubo, Umezawa (2007) \"The subunit composition of hinokiresinol synthase controls geometrical selectivity in norlignan formation\" PNAS 104: 21008-21013
\uff0a\uff14, Yamamura, Suzuki, Hattori, Umezawa (2010) \"Subunit composition of hinokiresinol synthase controls enantiomeric selectivity in hinokiresinol formation\" Org Biomol Chem 8: 1106-1110<\/pre>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n
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\u3000<\/a><\/p>\n\n\n\n
\u6709\u7528\u751f\u7406\u6d3b\u6027\u6210\u5206\u30ea\u30b0\u30ca\u30f3\u306e\u751f\u5408\u6210\u7814\u7a76<\/strong><\/h2>\n\n\n\n
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\u3000\u3000\u30ea\u30b0\u30ca\u30f3\u306f\u690d\u7269\u754c\u306b\u5e83\u304f\u5206\u5e03\u3059\u308b\u5316\u5408\u7269\u7fa4\u3067\u3042\u308a, \u305d\u306e\u4e2d\u306b\u306f\u69d8\u3005\u306a\u751f\u7406\u6d3b\u6027\u3092\u793a\u3059\u7269\u8cea\u304c\u591a\u304f\u5831\u544a\u3055\u308c\u3066\u3044\u308b. \u3044\u304f\u3064\u304b\u306e\u30ea\u30b0\u30ca\u30f3\u306f\u6297\u816b\u760d\u6027\u6d3b\u6027\u3092\u793a\u3059\u3082\u306e\u304c\u3042\u308a, \u7279\u306b\u30dd\u30c9\u30d5\u30a3\u30ed\u30c8\u30ad\u30b7\u30f3\u306f\u73fe\u5728\u81e8\u5e8a\u7684\u306b\u4f7f\u7528\u3055\u308c\u3066\u3044\u308b\u6297\u304c\u3093\u5264\u30a8\u30c8\u30dd\u30b7\u30c9\u306e\u539f\u6599\u3068\u3057\u3066\u5229\u7528\u3055\u308c\u3066\u3044\u307e\u3059. \u30dd\u30c9\u30d5\u30a3\u30ed\u30c8\u30ad\u30b7\u30f3\u3092\u7523\u751f\u3059\u308b\u690d\u7269\u7a2e\uff08\u30d2\u30de\u30e9\u30e4\u30cf\u30c3\u30ab\u30af\u30ec\u30f3\u306a\u3069\uff09\u306f\u9650\u3089\u308c\u3066\u304a\u308a, \u3055\u3089\u306b\u306f\u6297\u304c\u3093\u5264\u539f\u6599\u3068\u3057\u3066\u4e71\u7372\u3055\u308c\u305f\u3053\u3068\u304b\u3089, \u690d\u7269\u306e\u500b\u4f53\u6570\u304c\u6fc0\u6e1b\u3057\u305f\u904e\u53bb\u304c\u3042\u308a\u307e\u3059.  \u3053\u308c\u3089\u690d\u7269\u306f\u683d\u57f9\u304c\u5bb9\u6613\u3067\u306a\u304f\u5b89\u5b9a\u4f9b\u7d66\u306f\u96e3\u3057\u3044\u3068\u3055\u308c\u3066\u304a\u308a, \u8fd1\u5e74\u3067\u306f\u5fae\u751f\u7269\u306a\u3069\u3092\u7528\u3044\u305f\u751f\u7269\u5de5\u5b66\u7684\u624b\u6cd5\u306b\u3088\u308b\u30dd\u30c9\u30d5\u30a3\u30ed\u30c8\u30ad\u30b7\u30f3\u306e\u5b89\u5b9a\u30fb\u5927\u91cf\u751f\u7523\u306b\u5411\u3051, \u7814\u7a76\u304c\u6d3b\u767a\u306b\u3055\u308c\u3066\u3044\u307e\u3059. 
\u3000\u3000\u30dd\u30c9\u30d5\u30a3\u30ed\u30c8\u30ad\u30b7\u30f3\u306e\u751f\u5408\u6210\u7d4c\u8def\u306f\u690d\u7269\u306b\u3088\u3063\u3066\u7570\u306a\u3063\u3066\u304a\u308a, \u5f53\u7814\u7a76\u5ba4\u306f, \u4eac\u90fd\u5927\u5b66\u751f\u5b58\u570f\u7814\u7a76\u6240\u306e\u6885\u6fa4\u7814\u7a76\u5ba4\uff08\u73fe\u30fb\u98db\u677e\u7814\u7a76\u5ba4\uff09\u3068\u5171\u540c\u3067, \u30dd\u30c9\u30d5\u30a3\u30ed\u30c8\u30ad\u30b7\u30f3\u7523\u751f\u690d\u7269\u306e\uff11\u3064\u3067\u3042\u308b\u30bb\u30ea\u79d1\u306e\u30b7\u30e3\u30af\uff08Anthriscus sylvestris\uff09\u3092\u30e2\u30c7\u30eb\u690d\u7269\u306b\u7528\u3044\u3066, \u6297\u816b\u760d\u6027\u30ea\u30b0\u30ca\u30f3\u306e\u751f\u5408\u6210\u7814\u7a76\u306b\u53d6\u308a\u7d44\u3093\u3067\u304a\u308a, \u3053\u308c\u307e\u3067\u306b\u6570\u591a\u304f\u306e\u95a2\u9023\u907a\u4f1d\u5b50\u306e\u540c\u5b9a\u306b\u6210\u529f\u3057\u3066\u3044\u307e\u3059\uff08\u5f15\u7528\u6587\u732e\uff0a1-4\uff09. \u5c06\u6765\u7684\u306b\u30dd\u30c9\u30d5\u30a3\u30ed\u30c8\u30ad\u30b7\u30f3\u306e\u3088\u308a\u52b9\u7387\u7684\u306a\u751f\u7269\u5de5\u5b66\u7684\u751f\u7523\u306b\u5411\u3051, \u591a\u304f\u306e\u30ea\u30b0\u30ca\u30f3\u751f\u5408\u6210\u907a\u4f1d\u5b50\u306e\u60c5\u5831\u3092\u84c4\u7a4d\u3057\u53cd\u5fdc\u7cfb\u3092\u6700\u9069\u5316\u3059\u308b\u305f\u3081, \u73fe\u5728\u3082\u30b7\u30e3\u30af\u306e\u307f\u306a\u3089\u305a\u69d8\u3005\u306a\u690d\u7269\u7a2e\u304b\u3089\u30ea\u30b0\u30ca\u30f3\u751f\u5408\u6210\u907a\u4f1d\u5b50\u306e\u540c\u5b9a\u3092\u8a66\u307f\u3066\u3044\u307e\u3059.<\/pre>\n\n\n\n
\u5f15\u7528\u6587\u732e
\uff0a\uff11, Umezawa, Ragamustari, Nakatsubo, Wada, Li, Yamamura, Sakakibara, Hattori, Suzuki, Chiang (2013) \"A lignan O-methyltransferase catalyzing the regioselective methylation of matairesinol in Carthamus tinctorius\" Plant Biotechnol 30: 97-109
\uff0a\uff12, Ragamustari, Nakatsubo, Hattori, Ono, Kitamura, Suzuki, Yamamura, Umezawa (2013) \"A novel O-methyltransferase involved in the first methylation step of yatein biosynthesis from matairesinol in Anthriscus sylvestris\" Plant Biotechnol 30: 375-384
\uff0a\uff13, Yamamura, Kumatani, Shiraishi, Matsuura, Kobayashi, Suzuki, Kawamura, Satake, Ragamustari, Suzuki, Suzuki, Shibata, Kawai, Ono, Umezawa (2023) \"Two O-methyltransferases from phylogenetically unrelated Cow Parsley (Anthriscus sylvestris) and Hinoki-Asunaro (Thujopsis dolabrata var. handae) as a signature of lineage-specific evolution in lignan biosynthesis\" Plant Cell Physiol 64: 124-147
\uff0a\uff14, Kobayashi, Yamamura, Mikami, Sdhiraishi, Kumatani, Satake, Ono, Umezawa (2023) \"Anthriscus sylvestris deoxypodophyllotoxin synthase involved in the podophyllotoxin biosynthesis\" Plant Cell Physiol 64: 1436-1448<\/pre>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n
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